PreVu Introduction

PreVu® - A New Test for Canadians

The PreVu® Non-Invasive Skin Cholesterol Point of Care (POC) Test is a Canadian developed technology designed to measure cholesterol in the skin as a completely new way of helping to determine an individual's risk of coronary artery disease (CAD).

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The groundbreaking PreVu POC Test is:

Some of the most important centres of cardiovascular research in the world have been involved in clinical studies related to Skin Cholesterol as a new biomarker for risk of CAD and the PreVu POC Test designed to measure it. The PreVu POC Test has been registered and/or received clearance for sale and distribution in a number of regulatory jurisdictions and can be sold in Canada, the United States and within various Member States in the European Union.

Coronary artery disease (CAD) is the leading cause of death in Canada and a notoriously difficult condition for healthcare professionals to try and detect. And with so many Canadians failing to access, or even having access to healthcare professionals on a regular basis, large numbers remain dangerously unaware of the significant risk for a coronary event that they may be living with.

The coronary incident and survival statistics for Canadians are striking1:

In addition to this, at least 25% of patients with sudden death or nonfatal myocardial infarction have no prior symptoms whatsoever.2

Many of these first events, if not fatal, are disabling and/or require lengthy and costly medical care. At the same time, the evidence that most cardiovascular disease is actually preventable continues to strengthen.

The PreVu POC Test does not diagnose the presence or absence of angiographic CAD, but in less than 5 minutes it can rapidly and non-invasively uncover individuals who may possess hidden, high levels of risk of CAD towards helping them guard against that crucial heart attack.

In addition to this, the 5-minute PreVu POC Test can serve to start Canadians down or back down the path to more fully understanding their global risk for CAD - a small investment of time and attention to begin a process that could help improve the quality of your life and possibly save it.

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Elevated Skin Cholesterol and Risk of Coronary Artery Disease

Skin cholesterol has been shown in clinical trials to be strongly associated with significant CAD as measured by treadmill stress testing, coronary angiography, coronary calcium, carotid artery thickening, and carotid artery plaque.

In fact, individuals with elevated Skin Cholesterol levels have been shown to have a much greater risk of scoring an abnormal result in these respected and widely utilized cardiovascular tests (see the chart below).

Risk of Abnormal clinical Cardiovascular Test with Elevated Skin Cholesterol Test Measures If Test Result Abnormal
2.6 times greater risk
of abnormal Treadmill Stress Test
Functional cardiovascular disease Possible coronary artery disease
1.4 times greater risk
of abnormal Coronary Angiography
Coronary artery atherosclerosis Blockage of coronary arteries
3.0 times greater risk
of abnormal Coronary Calcium
Calcified coronary plaque Higher risk of future cardiac events
2.0 times greater risk
of abnormal Carotid Ultrasound (IMT)
Carotid artery atherosclerosis Increased risk of heart attack and stroke
3.0 times greater risk
of abnormal Carotid Ultrasound (Plaque)
Carotid artery atherosclerosis Increased risk of heart attack and stroke

Most patients who develop CAD have at least one major risk factor2 such as:

Guidelines recommend that risk factor assessment in adults should begin as early as age 20 and that all adults who are 40 or over should know their absolute risk of developing CAD.3

Consequently, if patients at higher risk for developing CAD can be identified earlier in the course of their illness, it is not unreasonable to expect improved outcomes towards guarding against that crucial first heart attack event if they can receive targeted and effective primary prevention measures.

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Extend Your Hand - Take the Test

PreVu has been developed for delivery across Canada through coronary artery disease risk assessment clinics in your neighborhood pharmacies and shopping malls, as well as in healthcare clinics, doctors' offices, and through many other public and private cardiovascular risk assessment testing venues. Be sure to ask your local healthcare professionals when PreVu will be available in your community.

Develop a clearer view of your risk of CAD... take the PreVu POC Test and spend five minutes that could start you down a road to a longer and higher quality life by coming to more fully understand your global risk of coronary artery disease.

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  1. Heart and Stroke Foundation of Canada
  2. Greenland P, Smith SC, Grundy SM. Improving coronary heart disease risk assessment in asymptomatic people: Role of traditional risk factors and non-invasive cardiovascular tests. Circulation 2001;104:1863-67
  3. Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Executive Summary; NHLBI 2001.